RAF Typhoon FGR4s have joined forces with France's air force in a combined operation on an hidden munitions depot in Syria operated by the Islamic State group (IS), per a report from the UK Ministry of Defence.
The site, identified by intelligence, was assessed as housing weapons and explosive materials, the statement said, and was positioned in mountains just north of the ancient city of Palmyra in Syria's central region.
"The RAF jets employed Paveway IV guided bombs to target a number of access tunnels down to the depot... early reports indicate the objective was successfully hit," the MoD said.
There was no evidence of any civilian impact in the strike on Saturday evening and every plane involved made a safe return, the MoD added.
The British jets were backed up by a Voyager tanker plane.
Daesh - alternatively referred to as Daesh - imposed jihadist rule over parts of Iraq and Syria until 2019.
"This operation underscores the UK's leading role, and resolve to work closely with allied nations, to eradicate any resurgence of Daesh and their harmful and extremist ideologies in the region," Britain's Defence Chief the Defence Secretary stated.
RAF aircraft have performed patrols over Syrian airspace to "prevent any attempted comeback" of Islamic State following its defeat at the battle of Baghuz in 2019, the authorities noted.
"I must thank all the members of our armed forces who took part in this strike for their skill and their bravery," the Defence Secretary added. "They were part of thousands of UK service members deployed over the festive period. This action, to take out dangerous terrorists who pose a risk to our security, highlights how UK forces are always on standby, all year round, keeping Britain secure within its borders and strong abroad."
Last December, the United States armed forces carried out what it termed a "large-scale strike" against Islamic State objectives in the country, following an assault resulted in the deaths of two US troops and a local interpreter in the Palmyra area.
The United Nations says Islamic State still maintains between 5,000 and 7,000 militants in Iraq and Syria.